What hormone inhibits iron absorption and increases in response to exercise?

Prepare for the Board Certified Specialist in Sports Dietetics Exam. Utilize flashcards and multiple-choice questions with hints and explanations. Ace your test!

Hepcidin is the correct answer because it plays a crucial role in the regulation of iron metabolism in the body. This peptide hormone is produced by the liver and is known to inhibit iron absorption from the diet by binding to ferroportin, the protein responsible for transporting iron from inside intestinal cells into the bloodstream. When hepcidin levels are elevated, iron absorption from the gut decreases, and iron release from stores is also impaired.

In response to exercise, hepcidin levels are known to increase, likely as a protective mechanism to prevent iron overload or to respond to changes in iron demand that can occur during physical activity. Exercise can induce factors that lead to the release of hepcidin, such as inflammatory cytokines, which further emphasizes its role in iron regulation, especially in athletes and individuals engaging in regular physical activity.

Understanding the function of hepcidin is critical for those working in sports dietetics, as it informs dietary recommendations related to iron intake for athletes who may be at risk for deficiencies, particularly endurance athletes or those undergoing intensive training.

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